Toxicity and health threats of phthalate esters: review of the literature.

poly(vinyl chloride) (PVC) plasticized with EDHadEven thoug ther reports had implied that certain formulations of PVC medical tubings (2,3) and containers would, in fact, release plasticizers as well as additives to solutions, little concern had been expressed as to the possible health consequences to humans from leaching of these agents. Since Jaeger and Rubin's publication, however, considerable interest has developed conceming the possible toxicogenic effects not only of DEHP, but of all hthalate esters. More recently, interest has lso cen O the potential hazards from these plasticizers in the environment. It is estimated that the